Well gambling like we all know is very unpredictable and anything can happen. I've heard of several stories where people hit some crazy ass multipliers and won a mighty jackpot, but this stuffs often happen unexpectedly, it's not something you plan for or work towards. If you're lucky, you might just be able to hit such crazy ass multipliers. So yes, it's very possible but not something we see everyday.
Probably those people who telling us that getting crazy win was promoting the site to play there, for me as long as the site is legit and there are many games inside I won't look for big jackpot to hit myself from turning a dollar to x10000. Beware for those people always flex their big win in the internet it will fade your excitement when you're eager to bet in a game.