Responsible risk is a phrases widely used in many sectors. For gambling responsible risks are the best you make with your self will without any influence. Making bets when intoxicated, or on high stress, rage betting are examples of how you could be gambling irresponsibly.
Some may argue that seeking for low chance bets is irresponsible but it's not as the low chance bets have higher multiplier. It may be a long shot but it'd not irresponsible as it's similar to betting on high chance outcome which gives less multiplier and you get a small portion of your bet. The risks on both case are same.