Both are profitable, but I think the ones that make the most money are in the trading industry.
After a quick research, Binance stated they have an annual profit of $14 billion, which I think casinos haven't reached that amount.
https://www.businessofapps.com/data/binance-statistics/IMO, these gambling casinos can enjoy higher profit margins per transaction due to the house edge, making them potentially lucrative on a smaller scale. Facing regulatory might is one of their problem.
I wanted to agree because the percentage of people trading is very high now but considering the fact that a lot of traders are still gamblers means that the casino has more engagements and they make more money than the trading industry. Remember that traders operate with a sense of discipline, traders exercise more self-control than gamblers, this is the reason why casinos make more money on a daily basis