It's simple OP, have a solid Backup fund, and by backup funds, it should include emergency fund, reserve and float funds. These funds offers you financial cushion covers whenever you have financial needs, because the major reason why investors are mostly tempted to sell off their coins is due to emergencies, when an emergency arises and there's no backup fund to cover those emergencies, then certainly, the next option would be to dip into your investment for financial backup.

Another reason that'll make investors feel tempted to liquidate their investment would be to diversify to other investments, which I wouldn't recommend, especially when they're still in their accumulation stage, except maybe they've actually reached an overaccumulation.