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I think if I am not mistakenly I have came across such discussion here in the forum, although I don't know how it was handled but I could remember someone say of self-exclusion and yet the account was still active and was continued to gamble on the account.
What mostly happened is that to me, I feels like the casino would have to give time or duration for automatic deactivation of that account, maybe they don't know if such user mistakenly click on self-exclusion without know the meaning of that and if such happened they could request for reactivation they still have little grace to have back their account. That is what I felt some casino doesn't go immediate effects to deactivate accounts.
If an account has been deactivated because it has been inactive for a long time and, prior to deactivation, the account was an active player who played honestly at a particular casino, the casino will consider deactivating the account even though it has not been active recently. This may fall under the exception category.
However, if an account is deactivated because it has been inactive for a long time and there is no history of deposit or withdrawal activity indicating that the account was active, I believe that if I were part of the team at a particular casino, I would also support the decision to deactivate such an account.