Logically, Leverkusen should have won this match more easily, since their ranking in the Bundesliga is higher than Hoffenheim’s. However, keep in mind that during their pre-season, Leverkusen were embarrassingly defeated by Flamengo’s U-20 team. That result shows it’s possible for Leverkusen to lose to Hoffenheim. or even if they were held to a draw by Hoffenheim, it would be quite embarrassing for them and ETH, since they played at their home ground.
Leverkusen has played against Hoffenheim many times and they're always the better team. In the last 5 games Hoffenheim hasn't been able to defeat Leverkusen therefore I think the game that's coming up is going to be in favour of Leverkusen still. Leverkusen will be planing on playing well this season to increase their chances of winning the season title. They need to go back to being favourite to winning regardless of teams like Bayern Munich and Dortmund being in the league. The league is open to all teams playing there and not meant for only one team. Any team that has the determination can end the season as the league winners and I think Leverkusen has a chance.