Yes, Real Madrid should be able to beat a club like Osasuna more easily because based on existing statistics, Real Madrid has an 80% chance of winning and if Real Madrid loses or draws, it means Xabi has not really improved the team's performance to be better, getting 3 points in the first match is very important to increase the team's confidence and if they lose it will embarrass Real Madrid as a top club even though Real Madrid already has good players in it and has also added ammunition, it should have a good impact.
The probability of Real winning is estimated by bookmakers as 1.21. If Real does not win, it will have nothing to do with the coach, players, etc. - fluctuations just happen sometimes. Personally, I added a Real Madrid win to my multi-bet with a handicap of -1 and odds of 1.62, I think this handicap will be easily covered.
The shittiest thing that could happen in this round has already happened - Atletico let us down as usual. I don't understand why this club is so bad. On paper they are no worse than Barcelona.