Newcastle didn't perform well in their first match against Aston Villa, so I wouldn't expect much from them against Liverpool.
Liverpool are a strong team and even one of the favorites to win the title this season. They also have a squad that's quite capable in all areas, so I wouldn't be surprised if Liverpool make a significant improvement in their performance in this match.
I'm still very confident that Liverpool can win their second match against Newcastle.
At the moment, bookmakers estimate the teams' chances as follows:
3.40 - 3.85 - 2.05
That is, in fact, Liverpool's chances of winning are estimated at 50%. Quite logical in my opinion, since in the last two games Liverpool conceded 2 goals in each. This is not a very good indicator for a favorite, is it? Newcastle are playing at home, plus maybe they will benefit from Isak's return or, conversely, his absence will bring the team closer together.