It's said about brain that, "use it or lose it" — now, question being, do you think if person plays brainless gambling games such as slots, dice for major part of his/her daily routine, will it make him/her dull?
The more research and analysis is done on these games, I think it is just waste of time. No skill is required for this game. Those who play such games do not have much effect on their brain. For long-term brain development, I think that such games should be selected that have the advantage of analysis. The more the brain follows a simple path, the more its performance will decrease. Of course, every gambler should exercise his brain properly.