Money matter can lead to separation everywhere including the family and gambling is money matter so it can surely lead to divorce. If a person is gambling irresponsibly and it's affecting the family's financial responsibilities this will cause problems in the home which can lead to divorce. A family person that gambles responsibly shouldn't have any financial problems in their home because of gambling. My wife knows that I gamble sometimes and I have assured her that I only use very small amounts for it so it doesn't affect our relationship.