Bayern being favorites is not even a debate at the moment. They have got a squad worth €857.5m. That is literally 2× Dortmund and ~2.5x Leverkusen. In addition, they can replace Coman or Gnabry with bench pieces such as it is nothing. And in the 6-0 vs Leipzig, they were winning possession in 11 seconds versus 27.5 by Leipzig, so they were effectively in the attacking third all night. Kane scores a hat-trick, Olise scores two and an assist, and Diaz scores...
But it is lazy to write Dortmund/Leverkusen off this early. Even when Mane had red card and Schlotterbeck + Sule were injured, Dortmund continued to create 1.63 xG versus St. Pauli. They are not hopeless. An even more striking example is the case of Leverkusen: they lost 1-1 but possessed 60% of the ball, 88% of the passes and yet they won xG (0.89 vs. 0.47). That does not mean tactical failure. So Bayern are favourites, but MD1 was more about variance penalising the chasers, than revealing them as dead
When a season in the Bundesliga starts like this, it means nothing good for that year. Leipzig, Leverkusen and Stuttgart all losing their game and Dortmund essentially losing it too after that comfortable lead. That is not a good sign and Bayern destroys Leipzig. Of course it is not the time yet to write the whole table in advance, but I think the chance that any team can compete with Bayern and maybe collect 80 points in the league is close to zero.
Leverkusen had a real peak and perfect conditions to play this one outstanding season. But now so many important people are gone. Coach gone, key players gone. And as you said, Bayern has options if they really need it. But the Bundesliga will be uncontested for them.