There are many chances that we can make sure that we can make some profits, but this isn't one of them. It's really risky and you can't just wait it out, if it's down then it's gone. So, there are cases where you can do spot trading, or lower leverage and the margin call would not be that easy, I would say take a look at those.

However, if you are a big trader who has done a lot of trades and usually in the profit then you know what you are doing and you won't be forced to do anything big, and you can definitely try 25x and probably will do a good job. It is not an easy thing, but it's not impossible neither. Those veterans could make this work somehow, and I am sure they are going to make a lot of good returns with this.