Casinos always make money as long as they have loyal followers and new users. Not all gamblers have the same mindset; some will stop using Bitcoin and opt for altcoins, but they will continue to play regardless of market conditions.

I've never seen a casino close down due to market fluctuations; instead, it's always been losing its reputation, with very few players coming in to play. It's the competition that beats them, and not the market conditions.