There's no definitive data to answer your question, as only the casino truly knows. I speculate that if a large number of Bitcoin gamblers lose and the casino keeps the Bitcoin from those gamblers losses, the casino could profit significantly from the Bitcoin price drop and wait for the price to rise again but is it likely that Bitcoin gamblers will gamble in such market conditions? Personally, I would reduce the frequency of using Bitcoin for gambling.
But I believe that regardless of whether the Bitcoin price rises or not the casino will still profit as this is a business.