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The Manchester Derby is a very tough one and there's always pressure from both ends, it's not about who has the best squad cause there are times when City had more better players but lost severally to Manchester United infact City is not in a good form recently and if they can't recover after the international break is over then Manchester United could take advantage of their situation.
Well both parties participated well in the transfer window and got major of their targets, Manchester United too still signed about 70% of their targets and failed to sign only a holding midfielder, that doesn't make them weak though, although the bookies would likely favour Manchester City more to win.
Well, I can’t vouch for either one of the Manchester clubs because City have not shown that they are a better team than they were last season and United are still finding the balance. So for me I think it is a 50:50 game in the derby, either sides could win. This game could also be the turning point for City when the league resumes you just can’t tell.
Judging from their previous games in let's say 10 years back, Manchester City had always had the upper hand so definitely the bookies will give them a lesser odds compared to Manchester United. Few years back, there was this game between these two clubs and Ten Hang was still in charge of Manchester United, City were of course the superior team, in that very match Manchester City scored first but at FT Manchester United won the match 2 - 1 after they scored two late goals. Again in the FA cup finals, of course City were also the favourites but at the the end United won the match. These are two notable that I brought to your notice, City has been the favourites to win among the two teams in recent years but sometimes surprises can be pulled that's why I'm agreeing with Satoprincess on the 50 : 50 for both clubs.