Bitcoins are continually being lost. People lose their wallet logins. People die without anybody else holding wallet logins. Bitcoins are burned for any number of reasons. All these things and more are reasons why bitcoins are lost, which all contribute to the value of the bitcoins that remain.
These have been happening for long, so it has become a bitter lesson to many of us, thereby making us wiser than them of old. Or are you not wiser than them already knowing fully well the danger of losing your Bitcoin in case something unplanned for happened? If you don't, I guess you should do. I believe that this understanding and taking precautions will not really make the loss of access to Bitcoin be the major reason why it will appreciate in price, but a true adoption and liquidity injection.
There is quite a possibility that, over time, AI programs will be created that can locate such lost wallets and, using powerful generative capabilities, retrieve the bitcoins from them. But then the question arises, if such a capability becomes available to people, wouldn’t it also be used for theft? I think that the knowledge of the existence of such wallets has already attracted many developers to the idea of creating such a capability.