PSG losing Ousmane Dembélé and Doue due to injury can be a problem to the squad, like we all know that these two guys are the key players of PSG and without them it will be tough in the pitch, the way they handle the flow of the game won't be as how these other guys you mentioned as replacement I'll. For me Barcola is someone that doesn't know how to finish the ball after creating chances to score, he really need to improve in that aspect, that's why I prefer Doue to him but as long as is PSG I don't think winning a game would be a problem but the goals won't be as many as we expect from them, good thing Ramos now have a chance to start a game.
PSG has been affected already after getting the information they Dembele was injured Doue is also another fantastic player both of them helped the PSG team last season to achieve all the victories and trophies they achieved but being injured now the manager will have to use the players I the team he may be lucky to see n improvement in the players that will cover their wing. The performance of PSG is no longer going to be the same especially in the champions League where they will face Atalanta and Barcelona if they can come out of the group stage then they will be happy to continue the knockout stage with their key players.