What i just understand is that if there is so much congestion in the mempool, your transaction is likely to attract higher fees and if you try to adjust the fees it means it will take longer for your transaction to be confirmed. If you want lower fees and fast transaction you have to check if there is less congestion in mempool.
Will executing a Bitcoin transaction (with Electrum) at the exact moment when the green transaction graph of
https://mempool.space/ reaches its lowest point result in lower fee?
To answer your question directly, it's a yes answer because it shows that there is less network activity in the mempool of which the fees will be lowered.