The match between AC Milan and Napoli is going to be a bit tensed. Milan is still unbeaten for the season and same as Napoli. I don't see AC Milan going through this game but don't forget the home advantage. Home fans may ginger up the team to victory. It's definitely going to be a goal-goal game and could possibly end in draw.
The two teams had a good transfer window and their additions have been influencial. It's going to be a midfield game between Modric and De Bruyne. I'm sure it would be a nice game to watch.
The point is that both teams are in great form, and with that, it is a very difficult match to predict. From my observation of how both teams are currently performing, I would say both teams have an equal opportunity to win this upcoming match, because the level of their performances seems to be the same. So, I will not be surprised if either Napoli or AC Milan wins this match. However, what I think the result might be is a draw.
Yes, sometimes the team that is hosting the game appears much stronger, and I am expecting that from AC Milan. But still, I will not say they are the favorites to win the game, because Napoli are currently strong both at home and away. Let’s just see what happens. Both teams have recently rebuilt their squads during the last transfer window. As you said, both sides have experienced midfielders the match will be very interesting from my point of view.