Cannot answer the profit question. Given the recent FPGA rumors, I guess you may have better odds when go with new X11 coins.

And I just followed Chris' call on Colorcoin. Again, I am late .... when I get there, it was just about 1hour after launch and difficulty was 22 already. Put 2 750Tis on solo, each around 1.5M without OC. Haven't seen any block yet. May allocate more cards there later but I don't see the potential of this coin yet.  Had mined Hirocoin with 290x in the past, but stopped that long time ago.  We'll see how x11 coins goes.  Now days all scrypt coins looks like "scam coins"... but look at numbers of x11 clones, I feel that it may fit in that category pretty soon. Maybe some devs with powerful FPGA just doing the scam pump and dump now. If you can ride the train and dump before them, you may make some profit.

As to Jackpot, I am surprised there are still so many people mines on it. May give it another try. I did not update the wallet in time and wasted quite some time on the wrong branch --- even at that time it was not even close to 6000 block forking yet.  I then stopped mining after wasted a couple of days. May consider switch back... :-).