Quarkcoin gained 500x value after block reward sunk to 32. Was at 50 satoshis for months, went to 25000 satoshis in 3 days.
http://www.cryptocoincharts.info/period-charts.php?period=1-year&resolution=day&pair=qrk-btc&market=cryptsy

I believe Qubitcoin will do the same very soon, not 1000x but quite a lot.