Each Neptune Cube uses a high-quality PCI-E connection and draws approximately 300 watts at its port300 x 5= 2100?

And did you see? The ports are fan-cooled!
These ports are fan-cooled and can handle the power, but make sure youre using high-quality PSU:s, connectors and cables. Be careful when inserting and removing connectors as wear and tear may damage connectors. The act of inserting/removing cable connectors into ports degrades connection surfaces every time its done and should be minimized.
That should really help the fires to grow quickly by feeding air directly to the hot spot.

Btw so the controller box will apparently draw a decent share of watts too...