What you are getting for this amount of money is anonymity and offshore protection.   The card is not in your name.   This is one way how wealthy people protect their liquid assets.    I think it is no unreasonable to have this high of a set up fee.  The people who use these cards load them up with a lot of cash.    To make it worthwhile someone would load the equivalent of $25k on these cards.   The bitcoin market isn't there yet but it will get there.   For one person to buy $25k on Mt. Gox would clear out the order book in th currrent market. 

What could happen now is that someone could create these cards with a lower price by leaving out the anonymity and offshore protection.   You would still have transaction fees but as you have said it will be worth it.   

I can envision a day when the wealthy people will load these cards with $100,000 worth of bitcoins iinstead of Euros and use that. At the rate bitcoin is increasing you may not be able to deplete the card.