I won't encounter any issues putting a OC'd and a stock Antminer on the same power supply?
Will the 2 different power draws effect anything?
I don't think it will, but I am a noob and trying to help out a friend, I don't want him to blow his house up.

It won't affect anything, as long as it can supply the right amount of amps @ 12v it'll be fine. Now if I remember rightly you need around 30 amps for each miner on the 12v rail. This is not the supply from the wall but what the power supply will push to the miner. Check the specs on the power supply there should be a sticker with the info on it.
Best type to use are the ones that have a single rail for 12v.
