Makes a lot of sense to separate commerce from content. LadyBytes thinking about the commerce end of the business is a sound one and will likely result in a higher caliber and classier outcome. 

Similarly, it makes a lot of sense to create woman's oriented content which is decidely different. For example one of the largest sales forces on earth is Avon, and women tend to be the most avid users of Facebook. Women also take the lead in the day-to-day purchase of food and clothing as well as healthcare. So clearly, BTCs need equal access to flourish.

Initially, makes sense to colocate, as the community grows, not so much.