Hosting
10 S3s, plus PSUs, lots of cabling, non-standard design
1 SP30, 1 network cable, 1 power cord, standard rack design
Advantage: SP30
For data center deployment, the SP30 is the flat out winner. The standard rack design works very well with high-density cabinets. There's only a single machine with a power cable and a network cable. The data center only needs to worry about managing a single IP address and providing remote access to the web-based configuration interface and direct SSH access can be controlled easily.
With the current price of Bitcoin SP30s hosting requirement may now be considered a disadvantage. In less than 90 days it wont even be able to pay the hosting fee
That's relevant to both the SP30 and the S3 equally. The advantage still goes to the SP30 regardless of what the price of BTC does. The SP30 requires less space and less power in the hosted environment.