I tried it and had the same experience. Minera doesn't work very well for me at all, ever. Regardless of version and any tweaks and regardless of what miner software I activate within Minera, it's low rate and higher than 95% HW errors.

I did discover that an Atom 450 based netbook running cgminerdmaxl with USB hubs can easily handle 10 ASICs, if that helps you any. I ran that way for a week, to see how it would go.

A quad AMD Phenom with the same setup does just fine and can handle even more ASICs.