On a regular basis, I spend Bitcoin on domain names through Namecheap. I also often purchase gift cards to Papa John's and CVS through Gyft.com, and use those to purchase things.
Whenever I travel with my family I buy my plane tickets, book my hotel, and rent a car with Bitcoin through cheapair.com.
When Bitcoin is rising in price, I tend to hedge my gains by purchasing precious metals through amagimetals.com.