They also originally stemmed from Al-Qaeda in Iraq, but they are mortal enemies of ISIS.
Al Nusra and the ISIS are not mortal enemies. For sure there are some differences between the two, but they are united by their common enemy (Bashar al Assad). And both the organisations receive funding from the Saudi and Qatari royal families, who exert a lot of influence over them. To this date, both the terrorist groups remain affiliated to the Al Qaeda.