Cpu is averaging above 195 hashes (i7-2600), absolutely no problems there.
Cpus hashing rate have always halved on last three or four N-factor changes. If I remember correctly my GPU rates were down a bit more on average.
But this time much more:

I am getting around 220 hashes/second stable with one thread on 4gb R7 240. Then got "declaring SICK" output on console and yacminer.exe crash after 6 hours. No other HW errors before that though.

Thirtybird, would you mind sharing your parameters?