Soon one of those Bitcoin ETFs will hit wallstreet and that will likely decide the price of bitcoin just like it does gold. Most of these exchanges will disappear since speculation with bitcoin will be much easier using the NYSE and be replaced by localbitcoins-like fixed rate exchanges to obtain the actual coins.
Possibly, although this does attack one of the core principles of bitcoin by requiring an intermediary. The danger with such a big and juicy intermediary like a BTC ETF is that it becomes a massive target for hackers, potentially compromising the whole system.
I think that we'll still see exchanges, but the introduction of ETFs will see massive consolidation among their ranks. This should result in better quality, more liquid and deeper exchanges, which is good news for everyone.