It's less resistant from a technical perspective. I'd expect the gap between ASICs and GPU to be about 10x wider for neoscrypt, compared with scrypt.

From a practical perspective, only minor alts are going to be using neoscrypt, so there isn't going to be any significant money to be made; and more importantly, many of the coins using neoscrypt are switching from another algo. If they've switched algo once, they're probably going to switch again, so again ASICs won't be useful.

Neoscrypt also has big disadvantages, in that it is very slow for CPUs. This makes verifying the blockchain much slower, and may make it impractical for mobile devices which are power constrained.

If you want your coin to be ASIC resistant, then the easiest way to do it is to say that you will change the PoW algo when and if you feel like it.