Since Slush has their Diff made to AUTOMATICALLY adjust, does this mean the S4 will be fine on Slush?
Every decent pool has their difficulty automatically adjust. The problem is that they all start at a base level and adjust up from there unless the user sets a minimum level/starting level (which most pools also have the ability to change). If the user keeps the minimum/starting level too low, the S4 will choke to death before it is adjusted to an adequate level.