Yeah Dogie, I have found that Bitmain and Rockminer products simply do not play well together. I have never been able to run any form of R-boxes on same computer as a bitmain device, the drivers just are not compatible somehow (even though the controller appears to be identical, go figure).
I actually had an R-Box and 2 Ant U2's running on the same machine for several months. Don't ask me how I did it. I messed with it forever and almost gave up and then it just started working. Again, don't know what I did... I uninstalled and re-installed drivers and Zadig'd and it just started working somehow. Unfortunately it stopped working when I messed with things trying to get the U3 working.