IMO there are too many risks using bitcoin to buy and/or sell a piece of real property. I don't think there are any/many title companies that will deal in terms of bitcoin when assisting with the transferring of title of a property so you would have no real guarantee that all the paperwork is being handled properly and that you would have clear title once you pay for the property
Well, although there are probably some extra difficulties in doing the main part of the transaction in Bitcoin, I highly doubt this is the first piece of US real estate that has transacted with a crypto currency. To be sure, the Title company (and some others) will want to be paid for their services in cash, but converting a small amount of BTC to do so ought to be fairly straightforward.
Regardless, let me ping my Realtor this week and get a complete and thorough description (and prices / or at least good estimates) of any and all things that may need some US cash to do the transaction correctly, and I'll post all of that up.