Volume is very important when it comes to cryptocurrency trading. Coins with high trade volume seems to have more better reliable price than those with low trade volume. Again, coins with really low trade volume are mostly scam coins or eventually turns out to be shit coins.
If I see a coin rising by the rate you said 40-60x , then honestly, I wouldn't regret at all if I didn't invest on those coins. That is some clear sign of manipulation taking place. I would instead be glad I didnt invest, since I am pretty much sure I wouldn't be able to sell the coins back later.