It's probably not so much your settings but the power distribution.
I have 4 x 290X running on a 1500W and had to try all kinds of PCI-E connector combinations on those cards to keep it running without crashing when 100%.
Those R9 cards pull a lot of power so make sure you don't put every card on one rail of your PSU.
My PSU has 5 rails and each has 2 PCI-E plugs on it, I had to use all 5 for the 4 cards.
Example:
Connector 1 of rail 1 in card 1 8-pin PCI-E
Connector 2 of rail 1 in card 2 6-pin PCI-E
Connector 1 of rail 2 in card 2 8-pin PCI-E
Connector 2 of rail 2 in card 1 6-pin PCI-E
Connector 1 of rail 3 in card 3 8-pin PCI-E
...and so on, it's not an exact science because I had to try some other combinations too, all of this also depending on your PSU quality.
Maybe that's the issue for you too

Thanks for the reply. I'm pretty sure each card has it's own rail. I'm using a couple modular PSUs. However, I do have the powered risers 2 risers per rail? Should they also have their own?
Is there a more efficient way to divide up the power I'm using? Maybe put 3 cards on one PSU and then the motherboard, hard drive, risers, and main GPU on the other PSU..?
Also, do I need to do anything with the main power line from the PSU that is NOT powering the motherboard?
I kinda jumped into all this without knowing too much about power/voltage. That probably wasn't the brightest idea.
Thanks again.