Just wanted to chip in with my 2c. Pointed 1.6 MH towards this pool, and an equal hashpower towards a DOGE pool. Over the past 24 hrs, got 7622 DOGE (slightly more than the estimated 7500 taking into account lower rig power at night), which translates to roughly 0,021 BTC at current Cryptsy rates. Over the same period, I earned a measly 0.0047 BTC in the coins that auto-sold plus an estimated of 0.0025 BTC in unsold coins at MegaMultiPool.
Summing up, mining DOGE directly I got 0,021 BTC while MMP gave me 0,0072 BTC over the same period - a third of that! Plus the uncertainty whether various altcoins I've been mining at MMP will sell at all.
The idea is great, the UI is great, autotrading makes a lot of sense... But in my case it simply doesn't work well. Perhaps MMP should only switch coins every few hours and sell them right away when they're still profitable rather than queue people up..? As I see it, the current way we end up with tiny amounts of each coin that is below the autotrading threshold and see our predicted profits drop after a coin switch.
Edit: just realized this is less than half of what I'd get mining even LTC directly (0.6074 LTC over 24 hrs according to CoinWarz vs ~0.2820 LTC I earned). Guess I'll be looking for greener pastures elsewhere... Have any of you done any apples-to-apples comparisons (ie. same time, same hashpower MMP vs something else)?