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I have a AMD 8 core FX CPU, 16GB RAM, 1 x R9-390-8GB and GTX980 Ti-6GB running on my PC.
If I put NH miner running 24x7, what would be the BTC payout per day?
Is it profitable to mine this way (ie. using NH) or better to mine individually vs multi-algo auto-mining?
I know this may sound basic questions but appreciate 2nd opinions.

Thanks

CPU will generate more heat and eat more energy but profit will be near zero. So better disable cpu mining in nicehash miner,
R9 390 and 980ti are good for mining and if you don't want to waste time learning all altcoin mining details then nicehash miner is good choice. BTC payout per day will vary, so just try for a day and you will see.

I just got around to experiment, and after running standard benchmark - the app smartly chosen the 390 for ETH and 980-Ti for algo/neoscrypt.
The dashboard says 6.5$ per day and global rate 13.2$ -- I assume after running this for day, I might catch up to global rate?
I disabled the CPU... after I see the payout of cents compares to dollars compared to GPU mining. Yes, the AMD 8-core does heat up.

I noticed the ETH mining uses sammy007 proxy. If I have another rig, could I point ETH mining to this proxy?

The Claymore miner does not support solo mining at the moment. So you cannot use it for the proxy.

According to Claymore, in the next release of the Dual miner, he will support the solo mining. So it is good news.

v4.2 Beta with Solo Mining mode is already out, and I am testing it now.