i have reinstalled windows twice, updated and removed drivers 3 times, once using DDU.
reinstalled what windows ? 3.1 / 95 / 98 / 2000 / win 7 / win 8 / win 10 
updated and removed what drivers ?
I have tried everything i can damn think of and still at a loss to know what exactly is causing the problem. And was wondering if any one here has had this issue or knows whats wrong.
Give us a full system spec , including driver versions , windows version , what miner software are u using
Are u using powered risers ?
Can you check the widows error logs ( event viewer ) and post it here ?
Shit sorry i posted the wrong draft... Windows 10, No powered risers as stated they are in the x16 slots directly on the mobo.
As for event viewer i cant post the whole event log however i recreated the problem and shows a 41 kernal-power system.
Driver version 22.19.162.4
As for mining software it happens on any one i use but using prospector v 07 on Skunk Hash