Oh right, my rig is gonna be 8 AMD cards, and 4 NVIDIA cards!

Will that be a massive problem?
How do I manage my devices? Can't I do it all on one monitor and use dummy plugs whilst managing the overclocking?
which is why 12 card rigs can be stupid
there are a few ways to do it
if you want to mine on nicehash
you can run multiple instances and setup the nvidia to one coin and the amd to another coin
but in the end both coins will be auto converted to btc.
I run a cpu and an amd on nicehash doing cryptonight
I then run a second instance for the 2 nvidia cards for zec
on one I check the cpu and the amd
on the other check the nvidia but in the end they all become btc
Okay... my 4 NVIDIA cards haven't arrived yet, and I can still amend the order...
Also, would it be easier to run 8 of the AMD cards on CryptoNight, and then the other 4 running Ethash?
I'm guessing that it'll still be better than having a mix of both AMD and NVIDIA on one rig?