The most reliable one is ETH I suppose and the safest one is Monero. I am sure that Monero is the most anonymous alt coin that we have now, there is not another competitive one on the cryptomarket yet, and about ETH it is clear I consider.
For me no other than Ethereum most reliable and safe one, it is tested and trusted of many people. Also ETH have huge potential to increase much more and become more profitable when years passed by. Even its having a not good price right now, I still believe
I would definitely agreed to trust Ethereum also as the best potential altcoin among all altcoins. Because this altcoin was already tested by many great investors with its potential huge profit when bullish market will take in effect. And I think there is nothing to worried about by its great deflation of its price because it has great possibity to easily recovered soon.