vh created an r606 branch to the cgminer compile.  perhaps try testing this branch. See this post for compiling instructions:

https://bitcointalk.org/index.php?topic=5053833.msg51597960#msg51597960

1. which mac are you on?  >About This Mac>System Report>Model Identifier  (e.g. MacPro5,1)

2. Do you get some sort of error message?

3. When the r606 is plugged into the mac, in the System Information app, does it show up as a device under Hardware>USB>USB Device Tree ?