PSG vs. Real, Villarreal vs. Juve, Atletico vs. ManU are very unpredictable pairs, I'll wait a real rumble there...In each other pairs I can see a clear favorite, excluding, maybe, Benfica vs. Ajax.
The PSG Vs Real Madrid match will be an interesting match. The two teams are in good shape. PSG are leading in the Ligue 1 standings, while Real Madrid on the other hand are also leading in the La Liga standings. Is quite hard to predict who wins, but I think many goals will probably be scored. Atletico Madrid will have a tough match against Manchester United. Atletico Madrid have to play this match carefully to avoid losing, Because Manchester United focus are mainly on their Champion League matches. However, the Round 16 will indeed be very interesting, and I can't wait.
I have a different view, when you say PSG v Madrid match there will probably be a lot of goals scored but to me it doesn't look like it will happen. I personally expect the match to be tough so both of them might be deadlocked to score goals but yeah, I think everyone has their own version of how many goals it can be said to be a lot of goals. Because if it's just two goals though for both teams, surely it's a meager amount of goals even though both teams are to score. Regarding Manchester United and Juventus, I believe both will win because if I look at their current conditions in their respective leagues, I believe on paper they will win.