You have think to add a way to send directly 3.3v or 5v on your stick without take power from USB and use USB just for data ?
They are powerful and efficient industrial power supply for low voltage and huge current.
It can be easy to cool if it's possible to align chip with a bigger radiator or waterblock system or use M.2 system to cool your chip

Like this :

So, the pod miners.
Also regarding soliciting funds from Sledge, that was tongue-in-cheek. We're doing okay, and I couldn't ask for better advertisement than his story anyway.