Last season RC Strasbourg beat Lyon with the same goal margin but this current game was different. Lyon was just fortunate to get that win because Strasbourg had better ball control and more goal attempts but it was not their lucky day. Strasbourg has not yet escaped relegation which was why this game was so important to them. But they have to take other matches more seriously because relegation will be a big blow to the club. They will lose sponsorship deals, players, and even fans. Last season under coach Peter Sylvester Bosz, Lyon ended the season in the eighth position, maybe Laurent Blanc could lead them to go the fifth position which gives them a ticket to Europa Conference League qualifiers.
I wouldn't say Lyon has "no" chance for Europe, there are still 6 more games left and there are just 3 point difference between Lyon and conference league as well. It means that they could end up winning and that could result with a much better result as well.
As long as they keep playing like this of course, we have seen them do so much better and I feel like that matters a lot. I know that it will not take a while before it could be like that, but I believe that the best thing for Lyon is to make sure they make some money, transfers are the best way to do it, but the hardest yet most profitable is Europe. Conference league doesn't pay that much but it's a start, they need to rank higher and get more money from the league and the conference league and use that money as a stepping stone to go towards making something else work for higher levels.