PSV can take some points against Sevilla or Lens, but I'm sure they won't manage to take any points against Arsenal. PSV can take advantage of the home game to play better against their visitors, they should be favored.
The second match in the group stage will take place in early October, Sevilla is the opponent. PSV, playing at home, will certainly take advantage of home advantage to win, but if Sevilla is able to put up a good fight then both teams will have difficulty winning the match. The possibility is may with PSV, but no one knows for sure what will happen.
Definitely PSV will secure a point from Sevilla or Lens but I think they stand a better chance with Lens as Seville looks like a better team as compared to Lens both in the UCL and their local league, Lens don't seem to have what it takes to take on PSV, Arsenal was so much of a strong team over PSV so they couldn't stand a chance but I don't see that with Lens.
Home advantage is also something PSV will not fail to utilize over Sevilla in their next UCL game. It will be the first time both team are meeting in the UCL this season, Sevilla had played 5 league games in the Spanish league where they have lost 3 won 1 and drew . Going by this record they don't look sound enough as a contender to PSV as PSV have better statistical results.
Lens have a worse record statistically, they have played five league game so far in the french league, they lost all three and drew the remaining two, they are yet to record a single win, I wonder how they will cope in the champions league where the pressure is even higher as compared to their local league. PSV is definitely going to take advantage of Lens to secure points in the champions league.