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This should be the case, in a team there must be a suitable replacement, because it is impossible for the main player to be able to play continuously throughout the season without being absent, and because of this, Ange Postecoglou must be able to make changes to the Tottenham team to stabilize their performance even though there are several injured players.
Against Fulham this weekend it shouldn't be a difficulty for Tottenham because they are playing at home and also the quality of the Fulham team is very different from Tottenham who are at the peak of their performance at the moment, so I also don't doubt that Tottenham will achieve victory.
Tottenham's main squad depth is good, but their substitutes are not so good. So far Tottenham are on track to fight for the title, but I don't give them much confidence as Liverpool, Arsenal and Manchester City look like they will get something big this season. I don't believe Tottenham could lead the standings until the first half was over, in fact I think they deserved 1 point against Liverpool if the referee's performance wasn't that controversial.
Fulham are a good and sometimes unpredictable team, so Ange Postecoglou should not underestimate them. Fulham could surprise everyone by beating Tottenham this week, but I believe Tottenham are the most likely favorites to win the match.