This is indeed hard match for Roma because during group stages Brighton performance is far better compared to them but we shouldn't be forget because Roma is the finalist of last season so i am sure they will not be easily to beated especially Roma under De Rossi has been showing significant progress and the latest is Roma can able to beat Torino yesterday in Serie A and about Brighton this team was unstable in Premier League but for Europa League and FA Cup Brighton still able to managed their consistency because in Europa League Brighton can advances to the round of 16 and in FA Cup Brighton can reach to 5th round
I have to says the chances for Roma and Brighton is 50:50 which mean both teams has equal chances to qualified and first match will be held in Olimpico stadium which is Roma home ground and if Brighton can able to get at least draw result at there i think second leg will be more easy for Brighton but i have been notice on Europa League under Mourinho Roma has fantastic records at their home because since October 2022 in this competition Roma still unbeatable during playing at their home so these records makes me thinking there is possibility for Roma to win this match moreover Roma under De Rossi can playing more attacking
There is truth in assessing the strength of Brighton and Roma, the chances of the two teams qualifying for the quarter finals are very balanced, because the strengths of the two teams do not seem to be much different. De Rossi managed to make Roma better, that was a good achievement at the start of his managerial career, I think if Morinho hadn't been fired Roma would have continued to decline until now. Meanwhile, Roma victory over Torino means they are very stable under De Rossi control. Roma is lucky because they will act as hosts first, but Brighton has good bargaining power because they come from the Premier League which is known to be more competitive.
In fact, the match between Roma versus Brighton is very difficult to predict, I agree with you, that their chances are 50/50. But we can look at their next domestic matches as a reference before the round of 16 of the Europa League rolls around, where Roma will face Monza, and Brighton will face Fulham. Personally, if given the choice I would choose to avoid betting on this match, because it is difficult to judge which team is more dominant among them. We'll see if strategy De Rossi will be successful or his Italian colleague De Zerbi will win the match.