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Agree. If we analyzed the current performance of Inter Milan and Atletico Madrid, it seems Atletico Madrid will be difficult to beat Inter Milan. Moreover, they have no Griezmann now, he got injured and doesn't know when he will return. We know that Griezmann has a big role on Atletico Madrid attacking, it is a big lose when Griezmann will be unavailable for the match. It becomes harder because Inter Milan has a very solid defense. As far as I know, Inter Milan seems the team that has a low conceded goals during this season. In Serie A, they only got 13 conceded goals until now.
With the current condition of Atletico Madrid, it seems the advantage of playing at home won't affect anything. After the defeat against Cadiz, I am getting doubtful that Atletico Madrid to have the chance against Inter Milan. If a small team like Cadiz can score 2 goals, Inter Milan ideally can do more. Inter Milan has a very productive attack during this season, they already score 70 goals in Serie A. It won't be hard to score many goals against Atletico Madrid if Simeone doesn't change Atletico Madrid tactics.
Griezmann has indeed been playing quite well this season and he was the most important attacker especially in the Champions League. His 5 goals in 7 games were an important contribution to their success so far. But now that they lost this game against Cadiz and might be playing without Griezmann, it would be a huge surprise if they knocked out Inter Milan.
Is it actually safe that Griezmann will be missing the game? The last information that I found was that it will be a close call, but it is still possible for Griezmann to be recovered until then.
Inter Milan is probably the best balanced team along with Real Madrid and Manchester City although I was quite surprised how close the game against RB Leipzig was.